What We Do
In the Synapse Proteomics Group, we are focused on answering fundamental questions, such as how does the brain work? And at the same time asking how a disease state can upset brain function. This fundamental knowledge is then applied to identify new potential drug targets.
Developing treatments for diseases requires knowledge of the genes involved, the proteins they code for and how to target those proteins with drugs to change the disease state. Specific extra knowledge is required to know the best way to attack the problem. We need knowledge of what the disease-related protein does and which enzymes and binding partners influence the protein function. The Synapse Proteomics Group uses advanced technology to identify enzyme pathways and map interacting protein partners for disease-related proteins.