Bioinformatics is the application of information technology to the study of biology and medicine. It is a multidisciplinary field combining biology, mathematics, statistics and computer science to unravel complex biological problems. CMRI has dedicated data scientists/bioinformatics scientists who collaborate with CMRI medical researchers to tailor software/computational solutions around specific research questions. Typically, CMRI bioinformaticians are engaged early with the experimental design and subsequently in transforming the acquired experimental and clinical data into relevant knowledge that may lead to actionable novel research findings, improvements to clinical decision-making or precision medicine.
CMRI bioinformaticians deal with a variety of research data, some of which include: genomics (genome-wide sequencing of DNA), epi-genomics (modifications to chromatin and DNA), transcriptomics (tissue and single cell RNA sequencing), proteomics (large scale identification and characterisation of proteins by mass spectrometry), pharmaco-omics (drug responses based on multiple -omics data) and cell imaging. CMRI medical data scientists/bioinformatics scientists also play a key role in driving initiatives to strengthen data science/bioinformatics research within the Westmead Research Hub by promoting training opportunities and seminars.
Members of the CMRI Bioinformatics team:
Erdahl Teber BAppSc BSc (Hons) PhD Senior Research Officer (Kids Cancer Alliance)
Emilie Wilkie BSc (Hons) MSc DIC Senior Research Assistant