Finding cures for children's genetic diseases


The Kids Cancer Alliance (KCA) brings together all childhood cancer research and clinical care in NSW under a single unified banner.

CMRI is a founding member.

Our alliance offers a unique opportunity for clinical and laboratory researchers, working to improve the outcomes and quality of life for children with cancer, to come together to make new discoveries and apply pre-clinical research more rapidly and with greater impact.

Through the KCA, our researchers will be able to make use of their discoveries statewide, so that new drugs and diagnostics can be employed in trials across NSW, reaching more children and improving the power of the research studies.

We also aim to provide better supportive care for children from remote NSW undergoing treatment in their community, and deliver a higher standard of care through our share-care partners in rural and regional NSW.

KCA partners: Sydney Children’s Hospital Randwick, the Children’s Hospital Westmead, John Hunter Children’s Hospital, Children’s Cancer Institute Australia (CCIA)Children’s Medical Research Institute (CMRI) and Kids Research Institute (KRI)

Confirmed Projects:

  • Consent, communication and decision making in early phase paediatric cancer trials.
  • Pharmacokinetic assessment, aimed at reducing toxicity and enhancing efficacy, in child cancer patients undergoing therapy.
  • Development of a KCA Clinical Trials Centre for Childhood Cancer
  • Factors determining success of early phase clinical trials in child cancer patients.
  • Predictive clinical and genetic factors for the side-effects of chemotherapy in children treated for acute lymphoblastic leukemia
  • Telomere Research Program: Measuring the length of chromosome ends to predict the effects of cancer treatment and bone marrow transplantation
  • Molecular profiling for factors predicting sensitivity or resistance to therapy in relapsed child cancer
  • Development of a best practice Model of Care for survivors of paediatric cancer.

Official KCA website: