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Research

Cell Cycle Unit

The Cell Cycle Unit studies normal cell division in order to understand what makes cancer cells grow out of control. We are also developing new anti-cancer treatments aimed at stopping cell division, especially in difficult to treat brain tumours.

The major focus of the Cell Cycle Unit is to precisely define the mechanisms regulating mitotic cell division. Understanding the molecular regulation of mitosis will provide important insight into cancer biology mechanisms. We have previously identified key proteins involved in mitotic progression and characterised how these proteins function in this process.

Current research focuses on understanding the network of proteins required for mitosis and how they cooperate. This will provide insight into the errors that occur during cell division that can contribute to the development of cancer.

“Understanding the complex process of mitotic cell division is fundamental to our understanding of how cancers develop.” - Megan Chircop

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