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  • Biomedical Proteomics Unit
    Biomedical Proteomics Unit

Biomedical Proteomics

Biomedical Proteomics at CMRI is a collaborative research resource that combines applied proteomics with the development of Mass Spectrometry (MS)-based qualitative and quantitative methods for protein identification and characterisation. The facility supports CMRI and the Westmead Research Hub, as well as collaborations with groups and individuals from around Australia and the world.

Proteomics is the ability to study proteins in our cells and tissues on a large scale as well as one at a time. The successful study of important cellular proteins depends largely on the experimental design and requires a great deal of careful planning.

The facility aids biomedical research groups and individuals by offering access to equipment and methodology as well as expertise in the assessment of feasibility and strategy development for projects and programs involving MS-based proteomics analysis.


The Biomedical Proteomics Facility

In 2009-11, CMRI undertook a full refurbishment and extensive upgrade of the facility. Major funding from the Cancer Institute NSW (CINSW), the Australian Research Council Linkage Infrastructure, Equipment and Facilities scheme (ARC LIEF), and the Ian Potter Foundation provided two MS systems for advanced phosphoproteomics research.

Four additional MS systems were purchased with generous funding from the Australian Cancer Research Foundation (ACRF) and the Ramaciotti Foundations to equip the new Australian Cancer Research Foundation Centre for Kinomics (ACRF-CFK). Currently the facility houses a total of seven state-of-the-art mass spectrometry systems providing a massive increase in capacity and capability. The acquisition of new, cutting-edge equipment has resulted in an immediate surge in interest and demand for access, opening opportunities for exciting new collaborations.

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Mass spectrometry equipment supplied by SCIEX.

For further information on accessing the facility and general enquiries, please contact Val Valova (vvalova@cmri.org.au).