Embryology Unit Publications

Key Publications

1. Tam PPL and Beddington RSP. (1987) The formation of mesodermal tissues in the mouse embryo during gastrulation and early organogenesis. Development, 99: 109-126.
   PMID: 3652985
2. Tam PPL and Steiner KS. (1999) Anterior patterning by synergistic activity of the early gastrula organizer and the anterior germ layer tissues of the mouse embryo. Development, 126: 5171-5179.
   PMID: 10529433
3. Hukriede NA, Tsang TE, Habas R, Khoo PL, Steiner K, Weeks DL, Tam PPL and Dawid IB. (2003) Conserved requirement of Lim1 function for cell movements during gastrulation. Dev. Cell, 4: 83-94.
   PMID: 12530965
4. Lewis SL, Khoo PL, De Young RA, Steiner K, Wilcock C, Mukhopadhyay M, Westphal H, Jamieson RV, Robb L and Tam PP. (2008) Dkk1 and Wnt3 interact to control head morphogenesis in the mouse. Development, 135: 1791-801.
   PMID: 18403408
5. Lyon MF, Jamieson RV, Perveen R, Glenister PH, Griffiths R, Boyd Y, Glimcher LH, Favor J, Munier F and Black GCM. (2003) A dominant mutation within the DNA-binding domain of the bZIP transcription factor Maf causes murine cataract and results in selective alteration in DNA binding. Hum. Mol. Genet., 12: 585-94.
   PMID: 12620964

Review Articles

1. Pera MF, Tam PP.  (2010) Extrinsic regulation of pluripotent stem cells.  Nature, 465 (7299): 713-20.
   PMID: 20535200
2. Rossant J, Tam PP. (2009) Blastocyst lineage formation, early embryonic asymmetries and axis patterning in the mouse. Development, 136: 701-13.
   PMID: 19201946
3. Mihelec M, St Heaps L, Flaherty M, Billson F, Rudduck C, Tam PP, Grigg JR, Peters GB, Jamieson RV. (2008) Chromosomal rearrangements and novel genes in disorders of eye development, cataract and glaucoma. Twin Res. Hum. Genet., 11: 412-21.
   PMID: 18637741
4. Lewis SL and Tam PPL. (2006) The definitive endoderm of the mouse embryo: Formation, cell fates and morphogenetic function. Dev. Dyn., 235: 2315-29.
   PMID: 16752393
5. Tam PPL, Loebel DAF and Tanaka SS. (2006) Building the mouse gastrula: signals, asymmetry and lineages. Curr. Opin. Genet. Dev., 16: 419-25.
   PMID: 16793258

Recent Publications

1. Williamson SL, Giudici L, Kilstrup-Nielsen C, Gold W, Pelka GJ, Tam PP, Grimm A, Prodi D, Landsberger N, Christodoulou J (2011). A novel transcript of cyclin-dependent kinase-like 5 (CDKL5) has an alternative C-terminus and is the predominant transcript in brain.
   Hum Genet. Epub Jul 12.
   PMID:21748340
2. Tanaka SS, Kojima Y, Yamaguchi YL, Nishinakamura R, Tam PP (2011). Impact of WNT signaling on tissue lineage differentiation in the early mouse embryo.
   Dev Growth Differ. doi: 10.1111/j.1440-169X.2011.01292.x.
   PMID: 21762130
3. Combes AN, Bowles J, Feng CW, Chiu HS, Khoo PL, Jackson A, Little MH, Tam PP, Koopman P (2011). Expression and Functional Analysis of Dkk1 during Early Gonadal Development. Sex Dev. 2011;5(3):124-30.
   PMID: 21654186
4. Stark Z, Storen R, Bennetts B, Savarirayan R and Jamieson RV (2011). Isolated hypogonadotropic hypogonadism with SOX2 mutation and anophthalmia/microphthalmia in offspring.  Eur. J. Hum. Genet., Epub Feb 16.
   PMID: 21326281
5. Pfister S, Jones VJ, Power M, Truisi GL, Khoo PL, Steiner KA, Kanai-Azuma M, Kanai Y, Tam PP and Loebel DA (2011).  Sox17-dependent gene expression and early heart and gut development in Sox17-deficient mouse embryos.  Int. J. Dev. Biol., 55: 45-58.
   PMID: 21305474
6. Fossat N, Jones V, Khoo PL, Bogani D, Hardy A, Steiner K, Mukhopadhyay M, Westphal H, Nolan PM, Arkell R and Tam PP. (2011) Stringent requirement of a proper level of canonical WNT signalling activity for head formation in mouse embryo. Development, 138: 667-76.
   PMID: 21228006
7. Tanaka SS, Yamaguchi YL, Steiner KA, Nakano T, Nishinakamura R, Kwan KM, Behringer RR, Tam PP.  (2010) Loss of Lhx1 activity impacts on the localization of primordial germ cells in the mouse. Dev. Dyn., 239: 2851-9.
   PMID: 20845430
8. Leung AW, Wong SY, Chan D, Tam PP, Cheah KS.  (2010) Loss of procollagen IIA from the anterior mesendoderm disrupts the development of mouse embryonic forebrain.  Dev. Dyn., 239: 2319-29.
   PMID: 20730911
9. Rivera-Pérez JA, Jones V, Tam PP.  (2010) Culture of whole mouse embryos at early postimplantation to organogenesis stages: developmental staging and methods.  Methods Enzymol., 476: 185-203.
   PMID: 20691867
10. Fath T, Agnes Chan YK, Vrhovski B, Clarke H, Curthoys N, Hook J, Lemckert F, Schevzov G, Tam P, Watson CM, Khoo PL, Gunning P.  (2010) New aspects of tropomyosin-regulated neuritogenesis revealed by the deletion of Tm5NM1 and 2.  Eur. J Cell Biol., 89: 489-98.
    PMID: 20223554 

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