Healthier kids, brighter futures

About Us

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  • Dr Christine Bolithio and her daughters
    Dr Christine Bolithio and her daughters
  • Sir Lorimer Dods
    Sir Lorimer Dods

How We’re Different

Not all research is the same

CMRI conducts fundamental (meaning fundamentally important) medical and biological research. We ask the difficult questions. What causes cancer? How do we stop it? Why does development go wrong and how can we prevent it? How does the brain work? Can what we’ve learned be put to use to treat cancer, epilepsy and genetic diseases?

Our task is to make the future better

CMRI scientists ask the difficult questions in order to gain the important answers. This knowledge enables us to light the spark of discovery and to create a healthier future for all children.


What we’ve accomplished in the last 20 years:

  • World-first project to revolutionise cancer diagnosis and personalise treatment planning within 7 years, part of the 'Moonshot' to end cancer
  • Found a single genetic defect can cause cleft lip and palate
  • Fate map of the early embryo to help us understand many developmental problems
  • Identification of the components of telomerase, which will be important for treating 85% of all cancers
  • Discovery of the Alternative Lengthening of Telomeres (ALT) mechanism, which can lead to treatments for the other 15% of cancers
  • Developing a blood test for ALT cancers that will allow physicians to diagnose and plan treatments for cancers such as aggressive glioblastoma brain tumours
  • Partnering with the Children’s Hospital Westmead on a cure for genetic liver disease, with clinical trials about to begin
  • Discovering and developing a new class of drugs for treating epilepsy
 

What we plan to accomplish in the next 20 years:

  • Develop epilepsy treatments that will help children (and adults) around the world
  • Develop new treatments for kidney disease and diabetes
  • Provide more gene therapy cures for rare genetic diseases in children
  • New treatments for infectious diseases
  • Telomere research to help us understand predisposition to disease
  • Find new and better treatments for every type of cancer